Foundation of the Ludwig Boltzmann Institute in Vienna
The Ludwig Boltzmann Institute Applied Diagnostics (lbi:ad) is a translational research institution combining a team of transdisciplinary scientists, academic and industrial partners from several countries. The primary goal is the identification and validation of novel “dual (modality) biomarkers” that combine molecular biology and imaging technologies allowing for minimal-invasive tumor diagnostics. We envision a novel concept of in vivo pathology, which enables a detailed and functional assessment of the tumor subtype on the basis of gene expression, mutation status, epigenetic characteristics, vascularisation, metabolomics, and expression of surface receptors and/or further molecular characteristics. These features will be assessed through a combined use of liquid biopsy biomarkers and multi-kit imaging tracers, which together will allow for a functional, real-time, sequential and minimal-invasive diagnostic approach.
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